Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery

Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery

Abstract Background Transthyretin and immunoglobulin light-chain amyloidoses cause amyloid deposition throughout various organ systems. Recent evidence suggests that soft tissue amyloid deposits may lead to orthopedic conditions before cardiac manifestations occur. Pharmacologic treatments reduce fu...

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Bibliographic Details
Main Authors: Austin E. Wininger, Brian M. Phelps, Jessica T. Le, Joshua D. Harris, Barry H. Trachtenberg, Shari R. Liberman
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Cardiac amyloidosis
Amyloid
Transthyretin
Immunoglobulin light-chain
Musculoskeletal soft tissue
Orthopedic surgery
Online Access:https://doi.org/10.1186/s12891-020-03912-z

Internet

https://doi.org/10.1186/s12891-020-03912-z

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