Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique

Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique

Zhong-Jie Lu,1 Qi Yu,2 Shui-Hong Zhou,2 Jun Fan,3 Li-Fang Shen,2 Yang-Yang Bao,2 Ting-Ting Wu,2 Min-Li Zhou,2 Ya-Ping Huang3 1Department of Radiotherapy, 2Department of Otolaryngology, 3State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of...

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Bibliographic Details
Main Authors: Lu ZJ, Yu Q, Zhou SH, Fan J, Shen LF, Bao YY, Wu TT, Zhou ML, Huang YP
Format: Article
Language:English
Published: Dove Medical Press 2019-03-01
Series:Cancer Management and Research
Subjects:
CRISPR/Cas9 system
glucose transporter-1
HEp-2 cells
hypoxia inducible factor-1α
PI3K/AKT/mTOR pathway
laryngeal carcinoma
Online Access:https://www.dovepress.com/construction-of-a-glut-1-and-hif-1alpha-gene-knockout-cell-model-in-he-peer-reviewed-article-CMAR

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https://www.dovepress.com/construction-of-a-glut-1-and-hif-1alpha-gene-knockout-cell-model-in-he-peer-reviewed-article-CMAR

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