Preventive Effects of Baclofen but Not Diazepam on Hippocampal Memory and Glucocorticoid Alterations After Prolonged Alcohol Withdrawal in Mice

Preventive Effects of Baclofen but Not Diazepam on Hippocampal Memory and Glucocorticoid Alterations After Prolonged Alcohol Withdrawal in Mice

Our study aims at comparing in C57/Bl male mice, the impact of repeated injections of baclofen (an agonist of GABAB receptor) or diazepam (a benzodiazepine acting through a positive allosteric modulation of GABAA receptor) administered during the alcohol-withdrawal period on hippocampus-dependent me...

Full description

Bibliographic Details
Main Authors: Henkous Nadia, Martins Fabienne, Christophe Pierard, Mons Nicole, Beracochea Daniel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Psychiatry
Subjects:
hippocampus
prefrontal cortex
ethanol
glucocorticoids
GABA
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.799225/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.799225/full

Similar Items