Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing

Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing

RNA ligases play important roles in repairing and circularizing RNAs post-transcriptionally. In this study, we generated an allelic knockout of ATP-dependent RNA ligase (Rnl) in the hyperthermophilic archaeon Thermococcus kodakarensis to identify its biological targets. A comparative analysis of cir...

Full description

Bibliographic Details
Main Authors: Yancheng Liu, Yuko Takagi, Milyadi Sugijanto, Kieu Duong My Nguyen, Akira Hirata, Hiroyuki Hori, C. Kiong Ho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
circular RNA
RNA ligase
thermococcus kodakarensis KOD1
rRNA processing
C/D box sRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.811548/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.811548/full

Similar Items