Sustained Delivery of Chondroitinase ABC from Hydrogel System
In the injured spinal cord, chondroitin sulfate proteoglycans (CSPGs) are the principal responsible of axon growth inhibition and they contribute to regenerative failure, promoting glial scar formation. Chondroitinase ABC (chABC) is known for being able to digest proteoglycans, thus degrading glial...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-03-01
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Series: | Journal of Functional Biomaterials |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-4983/3/1/199/ |