Influence of macrolide maintenance therapy and bacterial colonisation on exacerbation frequency and progression of COPD (COLUMBUS): Study protocol for a randomised controlled trial

Influence of macrolide maintenance therapy and bacterial colonisation on exacerbation frequency and progression of COPD (COLUMBUS): Study protocol for a randomised controlled trial

<p>Abstract</p> <p>Background</p> <p>Chronic obstructive pulmonary disease (COPD) is characterised by progressive development of airflow limitation that is poorly reversible. Because of a poor understanding of COPD pathogenesis, treatment is mostly symptomatic and new t...

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Bibliographic Details
Main Authors: Uzun Sevim, Djamin Remco S, Kluytmans JanAJW, Van’t Veer Nils E, Ermens Anton A M, Pelle Aline J, Mulder Paul, van der Eerden Menno M, Aerts JoachimGJV
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Trials
Subjects:
COPD
COPD exacerbation
Macrolide antibiotics
Long-term treatment
Antibiotic resistance
Online Access:http://www.trialsjournal.com/content/13/1/82

Internet

http://www.trialsjournal.com/content/13/1/82

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