Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality.

In HIV-infected individuals receiving suppressive antiretroviral therapy, the virus persists indefinitely in a reservoir of latently infected cells. The proliferation of these cells may contribute to the stability of the reservoir and thus to the lifelong persistence of HIV-1 in infected individuals...

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Bibliographic Details
Main Authors: Sarah B Laskey, Christopher W Pohlmeyer, Katherine M Bruner, Robert F Siliciano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005689&type=printable