Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGFβ

After exposure to an antigen, CD8 T cells reach a decision point about their fate: to become either short-lived effector cells (SLECs) or memory progenitor effector cells (MPECs). SLECs are specialized in providing an immediate effector function but have a shorter lifespan and lower proliferative ca...

Full description

Bibliographic Details
Main Authors: Jeremy A. O’Sullivan, Frederick J. Kohlhapp, Andrew Zloza, Lourdes Plaza-Rojas, Brianna Burke, Nickolai O. Dulin, José A. Guevara-Patiño
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3930