Uncoupling Protein 2 Increases Blood Pressure in DJ‐1 Knockout Mice

Uncoupling Protein 2 Increases Blood Pressure in DJ‐1 Knockout Mice

Background The redox‐sensitive chaperone DJ‐1 and uncoupling protein 2 are protective against mitochondrial oxidative stress. We previously reported that renal‐selective depletion and germline deletion of DJ‐1 increases blood pressure in mice. This study aimed to determine the mechanisms involved in...

Full description

Bibliographic Details
Main Authors: Carmen De Miguel, William C. Hamrick, Randee Sedaka, Sudha Jagarlamudi, Laureano D. Asico, Pedro A. Jose, Santiago Cuevas
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
DJ‐1
hypertension
oxidative stress
renal disease
Ucp2
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.011856

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.011856

Similar Items