NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differentiation and barrier function

NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differentiation and barrier function

Abstract Atopic dermatitis (AD) is a common chronic inflammatory skin disorder characterized by disrupted epidermal barrier function and aberrant immune responses. Despite recent developments in new therapeutics for AD, there is still a large unmet medical need for disease management due to the comp...

Full description

Bibliographic Details
Main Authors: Yeonhee Cho, Zhongzheng Cao, Xin Luo, Jennifer J. Tian, Renee R. Hukkanen, Rajaa Hussien, Belinda Cancilla, Priyanka Chowdhury, Fei Li, Shining Ma, Edward L. LaGory, Mark Schroeder, Amanda Dusenberry, Leslie Marshall, Jenn Hawkins, Menno van Lookeren Campagne, Yi Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07146-y

Internet

https://doi.org/10.1038/s41419-024-07146-y

Similar Items