Capsule Phase Microextraction Combined with Chemometrics for the HPLC Determination of Amphotericin B in Human Serum

Capsule Phase Microextraction Combined with Chemometrics for the HPLC Determination of Amphotericin B in Human Serum

This article discusses the use of a sorbent-based microextraction technique employing a capsule device to isolate amphotericin B (AMB) from human serum before analysis by high performance liquid chromatography (HPLC). AMB is a macrocyclic compound used for the treatment of invasive fungal infections...

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Bibliographic Details
Main Authors: Natalia Manousi, Anastasia Korpeti, Abuzar Kabir, Kenneth G. Furton, Constantinos K. Zacharis
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Separations
Subjects:
capsule phase microextraction
amphotericin B
HPLC
central composite design
validation
serum
Online Access:https://www.mdpi.com/2297-8739/9/12/433

Internet

https://www.mdpi.com/2297-8739/9/12/433

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