A seeded propagation of Cu,Zn-superoxide dismutase aggregates in amyotrophic lateral sclerosis
Abnormal accumulation of protein inclusions in motor neurons has been known as a major pathological change in amyotrophic lateral sclerosis (ALS). Increasing numbers of proteins including mutant Cu,Zn-superoxide dismutase (SOD1) have been identified as constituents of pathological inclusions in a f...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-03-01
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| Series: | Frontiers in Cellular Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00083/full |