Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives

Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives

This study explored the development of cross-linked gels to potentially provide a physical barrier to vaginal sperm transport for contraception. Two types of gels were formulated, a physically cross-linked iota-carrageenan (C<sub>i</sub>) phenylboronic acid functionalized hydroxylpropylm...

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Bibliographic Details
Main Authors: Ankit Rochani, Vivek Agrahari, Neelima Chandra, Onkar N. Singh, Timothy J. McCormick, Gustavo F. Doncel, Meredith R. Clark, Gagan Kaushal
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Polymers
Subjects:
contraceptive formulation
cross-linked gel
rheology
physical barrier
vaginal sperm transport
Online Access:https://www.mdpi.com/2073-4360/14/9/1728

Internet

https://www.mdpi.com/2073-4360/14/9/1728

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