siRNA against CD40 delivered via a fungal recognition receptor ameliorates murine acute graft‐versus‐host disease

Abstract Acute graft‐versus‐host disease (aGvHD) remains a major threat to a successful outcome after allogeneic hematopoietic stem cell transplantation (HSCT). Although antibody‐based targeting of the CD40/CD40 ligand costimulatory pathway can prevent aGvHD, side effects hampered their clinical app...

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Bibliographic Details
Main Authors: Beate Heissig, Yousef Salama, Masatoshi Tateno, Satoshi Takahashi, Koichi Hattori
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:eJHaem
Subjects:
Online Access:https://doi.org/10.1002/jha2.439