siRNA against CD40 delivered via a fungal recognition receptor ameliorates murine acute graft‐versus‐host disease
Abstract Acute graft‐versus‐host disease (aGvHD) remains a major threat to a successful outcome after allogeneic hematopoietic stem cell transplantation (HSCT). Although antibody‐based targeting of the CD40/CD40 ligand costimulatory pathway can prevent aGvHD, side effects hampered their clinical app...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-08-01
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Series: | eJHaem |
Subjects: | |
Online Access: | https://doi.org/10.1002/jha2.439 |