Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

<p>Abstract</p> <p>Background</p> <p>Hypoxia is associated with increased resistance to chemo- and radiation-therapy. Hyperoxic treatment (hyperbaric oxygen) has previously been shown to potentiate the effect of some forms of chemotherapy, and this has been ascribed to...

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Bibliographic Details
Main Authors: Salvesen Gerd S, Kolmannskog Odd, Tronstad Karl J, Moen Ingrid, Reed Rolf K, Stuhr Linda EB
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/446