In silico and experimental approaches for validating RNA editing events in transcriptomes

In silico and experimental approaches for validating RNA editing events in transcriptomes

As a typical RNA virus, SARS-CoV-2 is subjected to RNA editing in host cells. While some researchers believe that a traditional variant calling pipeline retrieves all true-positive RNA editing events from the transcriptome, others argue that conventional methods identify many false-positive sites. H...

תיאור מלא

מידע ביבליוגרפי
מחבר ראשי:	Lai Wei
פורמט:	Article
שפה:	English
יצא לאור:	Taylor & Francis Group 2024-12-01
סדרה:	RNA Biology
נושאים:	RNA editing SARS-CoV-2 in silico experiment validation
גישה מקוונת:	https://www.tandfonline.com/doi/10.1080/15476286.2024.2432729

פריטים דומים

Proof-of-concept for effective antiviral activity of an in silico designed decoy synthetic mRNA against SARS-CoV-2 in the Vero E6 cell-based infection model
מאת: Nofar Atari, et al.
יצא לאור: (2023-04-01)

In silico screening of drug inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase target
מאת: Thanh Tung Bui, et al.
יצא לאור: (2022-03-01)

In silico study of the flavonoid compound of Sauropus androgynus leaves ON RNA-Dependent RNA polymerase (RdRp) SARS-CoV-2
מאת: Aghnia Nabila Ananda, et al.
יצא לאור: (2024-06-01)

Ocular A-to-I RNA editing signatures associated with SARS-CoV-2 infection
מאת: Yun-Yun Jin, et al.
יצא לאור: (2024-05-01)

Cnicin as an Anti-SARS-CoV-2: An Integrated In Silico and In Vitro Approach for the Rapid Identification of Potential COVID-19 Therapeutics
מאת: Hani A. Alhadrami, et al.
יצא לאור: (2021-05-01)

RESIC: A Tool for Comprehensive Adenosine to Inosine RNA Editing Site Identification and Classification
מאת: Dean Light, et al.
יצא לאור: (2021-07-01)

In silico analysis and identification of honey flavonoids as potential inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase and main protease
מאת: Muhammad Abrar Yousaf
יצא לאור: (2022-06-01)

RNA editing in response to COVID-19 vaccines: unveiling dynamic epigenetic regulation of host immunity
מאת: Yun-Yun Jin, et al.
יצא לאור: (2024-09-01)

Repurposing of Doxycycline to Hinder the Viral Replication of SARS-CoV-2: From in silico to in vitro Validation
מאת: Rajaiah Alexpandi, et al.
יצא לאור: (2022-05-01)

Design of a multi-epitope vaccine using HA and M1 proteins from influenza and S, E, and M proteins from SARS-CoV-2 by in silico tools
מאת: Sharareh Jamali, et al.
יצא לאור: (2023-01-01)

2-Phenoxyacetamide derivatives as SARS-CoV-2 main protease inhibitor: In silico studies
מאת: Pandu Hariyono, et al.
יצא לאור: (2022-01-01)

Immunized mice naturally process in silico-derived peptides from the nucleocapsid of SARS-CoV-2
מאת: Mario Aldair Campos-Ruíz, et al.
יצא לאור: (2023-10-01)

Analysis and Identification of Bioactive Compounds of Cannabinoids in Silico for Inhibition of SARS-CoV-2 and SARS-CoV
מאת: Chenxiao Chen, et al.
יצא לאור: (2022-11-01)

Host-dependent C-to-U RNA editing in SARS-CoV-2 creates novel viral genes with optimized expressibility
מאת: Pirun Zhang, et al.
יצא לאור: (2024-10-01)

In silico prediction of siRNA to silence the SARS-CoV-2 omicron variant targeting BA.4, BA.5, BQ.1, BQ1.1. and XBB: an alternative to traditional therapeutics
מאת: Rahatul Islam, et al.
יצא לאור: (2023-08-01)

Immunogenic SARS-CoV-2 Epitopes: In Silico Study Towards Better Understanding of COVID-19 Disease—Paving the Way for Vaccine Development
מאת: Vipin Ranga, et al.
יצא לאור: (2020-07-01)

In silico design of quadruplex aptamers against the spike protein of SARS-CoV-2
מאת: Mandana Behbahani, et al.
יצא לאור: (2021-01-01)

Evaluation of Predicted siRNA as an Antiviral against MERS-CoV Targeting the Membrane Gene in the Vero Cell Line
מאת: Amany Y. El-Sayed, et al.
יצא לאור: (2023-10-01)

Antiviral Activity of Metabolites from Peruvian Plants against SARS-CoV-2: An In Silico Approach
מאת: Luis Daniel Goyzueta-Mamani, et al.
יצא לאור: (2021-06-01)

Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies
מאת: Dr Abdulrahman E. Koshak, et al.
יצא לאור: (2020-01-01)

Inhibitory potential of phytochemicals on five SARS-CoV-2 proteins: in silico evaluation of endemic plants of Bosnia and Herzegovina
מאת: Tarik Corbo, et al.
יצא לאור: (2023-03-01)

Spike protein of SARS-CoV-2 Omicron variant: An in-silico study evaluating spike interactions and immune evasion
מאת: Jose A. Jimenez Ruiz, et al.
יצא לאור: (2022-11-01)

An Immunoinformatics Approach for SARS-CoV-2 in Latam Populations and Multi-Epitope Vaccine Candidate Directed towards the World’s Population
מאת: Andrés Felipe Cuspoca, et al.
יצא לאור: (2021-06-01)

Synthesis of New Organoselenium-Based Succinanilic and Maleanilic Derivatives and In Silico Studies as Possible SARS-CoV-2 Main Protease Inhibitors
מאת: Saad Shaaban, et al.
יצא לאור: (2023-07-01)

Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases
מאת: Korina Karagianni, et al.
יצא לאור: (2024-03-01)

An in silico pipeline approach uncovers a potentially intricate network involving spike SARS-CoV-2 RNA, RNA vaccines, host RNA-binding proteins (RBPs), and host miRNAs at the cellular level
מאת: Massimiliano Chetta, et al.
יצא לאור: (2022-09-01)

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
מאת: Ujjwal Neogi, et al.
יצא לאור: (2020-04-01)

Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling
מאת: Mohammad M. Al-Sanea, et al.
יצא לאור: (2021-07-01)

Reduced A-to-I editing of endogenous Alu RNAs in lung after SARS-CoV-2 infection1
מאת: Philip S. Crooke, III, et al.
יצא לאור: (2021-01-01)

Detailed Molecular Interactions of Favipiravir with SARS-CoV-2, SARS-CoV, MERS-CoV, and Influenza Virus Polymerases In Silico
מאת: Mitsuru Sada, et al.
יצא לאור: (2020-10-01)

Unlocking the potential of in silico approach in designing antibodies against SARS-CoV-2
מאת: Tasshitra Subramaniam, et al.
יצא לאור: (2025-02-01)

In Silico Screening and Testing of FDA-Approved Small Molecules to Block SARS-CoV-2 Entry to the Host Cell by Inhibiting Spike Protein Cleavage
מאת: E. Sila Ozdemir, et al.
יצא לאור: (2022-05-01)

In Silico Design of Peptide-Based SARS-CoV-2 Fusion Inhibitors That Target WT and Mutant Versions of SARS-CoV-2 HR1 Domains
מאת: Shana V. Stoddard, et al.
יצא לאור: (2021-07-01)

In Silico Screening of Drugs That Target Different Forms of E Protein for Potential Treatment of COVID-19
מאת: Gema Lizbeth Ramírez Salinas, et al.
יצא לאור: (2023-02-01)

In silico study of intrinsic dynamics of full-length apo-ACE2 and RBD-ACE2 complex
מאת: Qing Liu, et al.
יצא לאור: (2021-01-01)

Quantifying RNA Editing in Deep Transcriptome Datasets
מאת: Claudio Lo Giudice, et al.
יצא לאור: (2020-03-01)

Validation of Rapid Antibody (IgM – IgG) Test Kit for SARS-CoV-2 Infection in Surabaya, Indonesia
מאת: Museyaroh Museyaroh, et al.
יצא לאור: (2022-10-01)

Unraveling C-to-U RNA editing events from direct RNA sequencing
מאת: Adriano Fonzino, et al.
יצא לאור: (2024-12-01)

In silico study of medicinal plants with cyclodextrin inclusion complex as the potential inhibitors against SARS-CoV-2 main protease (Mpro) and spike (S) receptor
מאת: Doni Dermawan, et al.
יצא לאור: (2021-01-01)

In Silico Virtual Screening of Marine Aldehyde Derivatives from Seaweeds against SARS-CoV-2
מאת: Nalae Kang, et al.
יצא לאור: (2022-06-01)