The multifaceted role of IL-12 in cancer
Interleukin-12 is a heterodimeric cytokine having many family members IL-23, IL-27, IL-35, and recently discovered IL-39, produced by macrophages and dendritic cells. IL-12 is an effector cytokine and engages in anti-tumor and many immunotherapies as IL-12 DNA expression, Th1 helper cells, and natur...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-10-01
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Series: | Advances in Cancer Biology - Metastasis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667394022000272 |