The multifaceted role of IL-12 in cancer

Interleukin-12 is a heterodimeric cytokine having many family members IL-23, IL-27, IL-35, and recently discovered IL-39, produced by macrophages and dendritic cells. IL-12 is an effector cytokine and engages in anti-tumor and many immunotherapies as IL-12 DNA expression, Th1 helper cells, and natur...

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Bibliographic Details
Main Authors: Um e Habiba, Mussarat Rafiq, Muhammad Babar Khawar, Bismillah Nazir, Gulfam Haider, Nadia Nazir
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394022000272