Denoising PCR-amplified metagenome data

<p>Abstract</p> <p>Background</p> <p>PCR amplification and high-throughput sequencing theoretically enable the characterization of the finest-scale diversity in natural microbial and viral populations, but each of these methods introduces random errors that are difficul...

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Bibliographic Details
Main Authors: Rosen Michael J, Callahan Benjamin J, Fisher Daniel S, Holmes Susan P
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/283