Aryl hydrocarbon receptor is a tumor promoter in MYCN-amplified neuroblastoma cells through suppression of differentiation

Aryl hydrocarbon receptor is a tumor promoter in MYCN-amplified neuroblastoma cells through suppression of differentiation

Summary: Neuroblastoma is the most common extracranial solid tumor in children. MYCN amplification is detected in almost half of high-risk cases and is associated with poorly differentiated tumors, poor patient prognosis and poor response to therapy, including retinoids. We identify the aryl hydroca...

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Bibliographic Details
Main Authors: Kanita A. Chaudhry, Justine J. Jacobi, Bryan M. Gillard, Ellen Karasik, Jeffrey C. Martin, Tatiane da Silva Fernandes, Edward Hurley, Maria Laura Feltri, Kristopher M. Attwood, Clare J. Twist, Dominic J. Smiraglia, Mark D. Long, Anna Bianchi-Smiraglia
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Cell biology
Stem cells research
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223023805

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http://www.sciencedirect.com/science/article/pii/S2589004223023805

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