MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation
Enhancers are often transcribed into non-coding RNAs called enhancer RNAs. Here the authors show that super enhancer generated seRNA-1 regulates the expression of nearby myoglobin (Mb) gene by binding to heterogeneous nuclear ribonucleoprotein L during myogenic differentiation.
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-13598-0 |