MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation
Enhancers are often transcribed into non-coding RNAs called enhancer RNAs. Here the authors show that super enhancer generated seRNA-1 regulates the expression of nearby myoglobin (Mb) gene by binding to heterogeneous nuclear ribonucleoprotein L during myogenic differentiation.
Bibliographic Details
| Main Authors: |
Yu Zhao,
Jiajian Zhou,
Liangqiang He,
Yuying Li,
Jie Yuan,
Kun Sun,
Xiaona Chen,
Xichen Bao,
Miguel A. Esteban,
Hao Sun,
Huating Wang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-13598-0
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