Improved Methods for Deamination-Based m6A Detection

N6-methyladenosine (m6A) is a critical regulator of gene expression and cellular function. Much of our knowledge of m6A has been enabled by the identification of m6A sites transcriptome-wide. However, global m6A profiling methods require high amounts of input RNA to accurately identify methylated RN...

Full description

Bibliographic Details
Main Authors: Huanyu Zhu, Xinhe Yin, Christopher L. Holley, Kate D. Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.888279/full