Secreted frizzled-related protein 5 protects against renal fibrosis by inhibiting Wnt/β-catenin pathway

Renal fibrosis (RF) is an important pathogenesis for renal function deterioration in chronic kidney disease. Secreted frizzled-related protein 5 (SFRP5) is an anti-fibrotic adipokine but its direct role on RF remains unknown. It was aimed to study the protective effect of SFRP5 against RF and interf...

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Bibliographic Details
Main Authors: Deng Dai, Tian Dongli, Wang Yahui, Bai Yu, Diao Zongli, Liu Wenhu
Format: Article
Language:English
Published: De Gruyter 2024-03-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-0934