ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain.

ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain.

p97/Valosin-containing protein (VCP) is a member of the AAA-ATPase family involved in many cellular processes including cell division, intracellular trafficking and extraction of misfolded proteins in endoplasmic reticulum-associated degradation (ERAD). It is a homohexamer with each subunit containi...

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Bibliographic Details
Main Authors: Wei Sheng Chia, Diana Xueqi Chia, Feng Rao, Shoshana Bar Nun, Susana Geifman Shochat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3513293?pdf=render

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http://europepmc.org/articles/PMC3513293?pdf=render

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