Protein kinase a dependent phosphorylation of apical membrane antigen 1 plays an important role in erythrocyte invasion by the malaria parasite.

Apicomplexan parasites are obligate intracellular parasites that infect a variety of hosts, causing significant diseases in livestock and humans. The invasive forms of the parasites invade their host cells by gliding motility, an active process driven by parasite adhesion proteins and molecular moto...

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Bibliographic Details
Main Authors: Kerstin Leykauf, Moritz Treeck, Paul R Gilson, Thomas Nebl, Thomas Braulke, Alan F Cowman, Tim W Gilberger, Brendan S Crabb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2880582?pdf=render