Cell Death Effects Induced by Sulforaphane and Allyl Isothiocyanate on P-Glycoprotein Positive and Negative Variants in L1210 Cells

Cell Death Effects Induced by Sulforaphane and Allyl Isothiocyanate on P-Glycoprotein Positive and Negative Variants in L1210 Cells

Variants of L1210 leukemia cells-namely, parental P-glycoprotein-negative S cells and R and T cells expressing P-glycoprotein, due to selection with vincristine and transfection with the human p-glycoprotein gene, respectively-were used. The responses of these cell variants to two naturally occurrin...

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Bibliographic Details
Main Authors: Szilvia Kontar, Denisa Imrichova, Anna Bertova, Katarina Mackova, Alexandra Poturnayova, Zdena Sulova, Albert Breier
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
P-glycoprotein/ABCB1
multidrug resistance
sulforaphane
allyl isothiocyanate
autophagy
LC3B
Online Access:https://www.mdpi.com/1420-3049/25/9/2093

Internet

https://www.mdpi.com/1420-3049/25/9/2093

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