MiR-200c reprograms fibroblasts to recapitulate the phenotype of CAFs in breast cancer progression

MiR-200c reprograms fibroblasts to recapitulate the phenotype of CAFs in breast cancer progression

Mesenchymal-epithelial plasticity driving cancer progression in cancer-associated fibroblasts (CAFs) is undetermined. This work identifies a subgroup of CAFs in human breast cancer exhibiting mesenchymal-to-epithelial transition (MET) or epithelial-like profile with high miR-200c expression. MiR-200...

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Bibliographic Details
Main Authors: Zhao Lin, Megan E. Roche, Víctor Díaz-Barros, Marina Domingo-Vidal, Diana Whitaker-Menezes, Madalina Tuluc, Guldeep Uppal, Jaime Caro, Joseph M. Curry, Ubaldo Martinez-Outschoorn
Format: Article
Language:English
Published: Shared Science Publishers OG 2024-03-01
Series:Cell Stress
Subjects:
oxidative stress
mir-200c
chromatin modification
senescence
nfκb-hif signaling
cancer immunology
immunotherapy
Online Access:http://www.cell-stress.com/researcharticles/2024a-lin-cell-stress/

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http://www.cell-stress.com/researcharticles/2024a-lin-cell-stress/

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