<named-content content-type="genus-species">Toxoplasma gondii</named-content> Dysregulates Barrier Function and Mechanotransduction Signaling in Human Endothelial Cells

<named-content content-type="genus-species">Toxoplasma gondii</named-content> Dysregulates Barrier Function and Mechanotransduction Signaling in Human Endothelial Cells

ABSTRACT Toxoplasma gondii can infect and replicate in vascular endothelial cells prior to entering host tissues. However, little is known about the molecular interactions at the parasite-endothelial cell interface. We demonstrate that T. gondii infection of primary human umbilical vein endothelial...

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Bibliographic Details
Main Authors: Armond L. Franklin-Murray, Sharmila Mallya, Allen Jankeel, Suhas Sureshchandra, Ilhem Messaoudi, Melissa B. Lodoen
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mSphere
Subjects:
Hippo signaling
Toxoplasma gondii
VE-cadherin
actin
endothelial cell
mechanotransduction
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00550-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00550-19

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