Using regulatory and epistatic networks to extend the findings of a genome scan: identifying the gene drivers of pigmentation in merino sheep.

Using regulatory and epistatic networks to extend the findings of a genome scan: identifying the gene drivers of pigmentation in merino sheep.

Extending genome wide association analysis by the inclusion of gene expression data may assist in the dissection of complex traits. We examined piebald, a pigmentation phenotype in both human and Merino sheep, by analysing multiple data types using a systems approach. First, a case control analysis...

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Bibliographic Details
Main Authors: Elsa García-Gámez, Antonio Reverter, Vicki Whan, Sean M McWilliam, Juan José Arranz, International Sheep Genomics Consortium, James Kijas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3119053?pdf=render

Internet

http://europepmc.org/articles/PMC3119053?pdf=render

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