Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists

Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists

Designs for scaffolded DNA origami nanostructures are commonly and minimally published as the list of DNA staple and scaffold sequences required. In nearly all cases, high-level editable design files (e.g. caDNAno) which generated the low-level sequences are not made available. This de facto ‘raw se...

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Bibliographic Details
Main Authors: Ben Shirt-Ediss, Jordan Connolly, Juan Elezgaray, Emanuela Torelli, Silvia Adriana Navarro, Jaume Bacardit, Natalio Krasnogor
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
DNA origami
DNA nanotechnology
Reverse engineering
Contact map
Constraint programming
Spring embedder
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023002490

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http://www.sciencedirect.com/science/article/pii/S2001037023002490

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