Sequence motifs capable of forming DNA stem–loop structures act as a replication diode
Calculating peak‐height ratios between single‐nucleotide polymorphisms (SNP) alleles in sequencing chromatograms is a practical method for estimating their copy number proportions (CNPs). However, it is surprising that sequencing DNA from different directions might yield different results. We analyz...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-07-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.12233 |