A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds.

Gene expression profiling of tumors is a successful tool for the discovery of new cancer biomarkers and potential targets for the development of new therapeutic strategies. Reliable profiling is preferably performed on fresh frozen (FF) tissues in which the quality of nucleic acids is better preserv...

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Bibliographic Details
Main Authors: Dana A M Mustafa, Anieta M Sieuwerts, Marcel Smid, Vania de Weerd, Marcel van der Weiden, Marion E Meijer-van Gelder, John W M Martens, John A Foekens, Johan M Kros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696787?pdf=render