Dual Molecular Design toward a Lysosome-Tagged AIEgen and Heavy-Atom-Free Photosensitizers for Hypoxic Cancer Photodynamic Therapy

Dual Molecular Design toward a Lysosome-Tagged AIEgen and Heavy-Atom-Free Photosensitizers for Hypoxic Cancer Photodynamic Therapy

To date, a large number of photosensitizers (PS) have introduced heavy atoms to improve the ISC process and <sup>1</sup>O<sub>2</sub> generation. However, they often show low efficiency in hypoxic conditions, aggregate states, and turn-off PDT in the dark. Besides that, the t...

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Bibliographic Details
Main Authors: Thanh Chung Pham, Thi Thuy Hang Hoang, Yeonghwan Choi, Seongman Lee, Sang-Woo Joo, Gun Kim, Dongwon Kim, Ok-Sang Jung, Songyi Lee
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biosensors
Subjects:
photosensitizer
photodynamic therapy
AIE fluorescent probe
lysosome-targeting
Online Access:https://www.mdpi.com/2079-6374/12/6/420

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https://www.mdpi.com/2079-6374/12/6/420

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