Influenza PB1-F2 Inhibits Avian MAVS Signaling

RIG-I plays an essential role in the duck innate immune response to influenza infection. RIG-I engages the critical adaptor protein mitochondrial antiviral signaling (MAVS) to activate the downstream signaling pathway. The influenza A virus non-structural protein PB1-F2 interacts with MAVS in human...

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Bibliographic Details
Main Authors: Yanna Xiao, Danyel Evseev, Chase A. Stevens, Adam Moghrabi, Domingo Miranzo-Navarro, Ximena Fleming-Canepa, David G. Tetrault, Katharine E. Magor
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/4/409