Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway

Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway

<i>Vibrio cholerae</i> is an important foodborne pathogen. Cholix cytotoxin (Cholix), produced by <i>V. cholerae</i>, is a novel eukaryotic elongation factor 2 (eEF2) adenosine diphosphate ribosyltransferase that causes host cell death by inhibiting protein synthesis. However...

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Bibliographic Details
Main Authors: Kazuya Ozaki, Hiyo Nagahara, Asaka Kawamura, Takashi Ohgita, Sachika Higashi, Kohei Ogura, Hiroyasu Tsutsuki, Sunao Iyoda, Atsushi Yokotani, Toshiyuki Yamaji, Joel Moss, Kinnosuke Yahiro
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Toxins
Subjects:
Cholix
cell death
extracellular vesicles pathway inhibitor
RNA-seq
JNK
Online Access:https://www.mdpi.com/2072-6651/16/9/380

Internet

https://www.mdpi.com/2072-6651/16/9/380

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