C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus

C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus

Porcine epidemic diarrhea virus (PEDV) is an emerging coronavirus which causes acute diarrhea and destroys gastrointestinal barrier function in neonatal pigs. Trefoil factor 1 (TFF1) is a protective peptide for maintaining the integrity of gastrointestinal mucosa and reducing intestinal inflammation...

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Bibliographic Details
Main Authors: Huan Qu, Qiufang Zong, Haifei Wang, Shenglong Wu, Demin Cai, Wenbin Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
TFF1
DNA methylation
C/EBPα
porcine epidemic diarrhea virus
intestinal epithelial barrier
coronavirus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.881289/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.881289/full

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