RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the physical properties and organizing principles that define G body formatio...

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Bibliographic Details
Main Authors: Gregory G Fuller, Ting Han, Mallory A Freeberg, James J Moresco, Amirhossein Ghanbari Niaki, Nathan P Roach, John R Yates III, Sua Myong, John K Kim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
glycolysis
hypoxia
RNA
phase separation
Online Access:https://elifesciences.org/articles/48480

Internet

https://elifesciences.org/articles/48480

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