Incorporating Covariates into Measures of Surrogate Paradox Risk

Clinical trials often collect intermediate or surrogate endpoints other than their true endpoint of interest. It is important that the treatment effect on the surrogate endpoint accurately predicts the treatment effect on the true endpoint. There are settings in which the proposed surrogate endpoint...

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Bibliographic Details
Main Authors: Fatema Shafie Khorassani, Jeremy M. G. Taylor, Niko Kaciroti, Michael R. Elliott
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Stats
Subjects:
Online Access:https://www.mdpi.com/2571-905X/6/1/20