Comparison of three-parameter kinetic model analysis to standard Patlak’s analysis in 18F-FDG PET imaging of lung cancer patients

Comparison of three-parameter kinetic model analysis to standard Patlak’s analysis in 18F-FDG PET imaging of lung cancer patients

Abstract Background Patlak’s graphical analysis can provide tracer net influx constant (Ki) with limitation of assuming irreversible tracer trapping, that is, release rate constant (kb) set to zero. We compared linear Patlak’s analysis to non-linear three-compartment three-parameter kinetic model an...

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Bibliographic Details
Main Authors: E. Laffon, M. L. Calcagni, G. Galli, A. Giordano, A. Capotosti, R. Marthan, L. Indovina
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:EJNMMI Research
Subjects:
18F-FDG PET
Patlak’s analysis
Reversible trapping
Uptake/release rate constant, lung cancer
Online Access:http://link.springer.com/article/10.1186/s13550-018-0369-5

Internet

http://link.springer.com/article/10.1186/s13550-018-0369-5

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