Modification of substrate specificity of l-arginine oxidase for detection of l-citrulline

Abstract Enzymatic detection of citrulline, a potential biomarker for various diseases, is beneficial. However, determining citrulline levels requires expensive instrumental analyses and complicated colorimetric assays. Although l-amino acid oxidase/dehydrogenase is widely used to detect l-amino aci...

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Bibliographic Details
Main Authors: Kei Yamamoto, Yosuke Masakari, Yasuko Araki, Atsushi Ichiyanagi, Kotaro Ito
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:AMB Express
Subjects:
Online Access:https://doi.org/10.1186/s13568-023-01636-6