Live imaging of microglia during sleeping sickness reveals early and heterogeneous inflammatory responses

Live imaging of microglia during sleeping sickness reveals early and heterogeneous inflammatory responses

IntroductionInvasion of the central nervous system (CNS) is the most serious consequence of Trypanosoma brucei infection, which causes sleeping sickness. Recent experimental data have revealed some more insights into the disease during the meningoencephalitic stage. However, detailed cellular proces...

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Bibliographic Details
Main Authors: Nestor L. Uzcategui, Sena Güçer, Cris Richter, Annika Speidel, Elizabeta Zirdum, Michael Duszenko, Olga Garaschuk, Katherine Figarella
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Trypanosoma brucei
microglia
meninges
inflammation
heterogeneous response
immune cell recruitment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1253648/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1253648/full

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