Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans

Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans

During development, neurons form synapses with their fate-determined targets. While we begin to elucidate the mechanisms by which extracellular ligand-receptor interactions enhance synapse specificity by inhibiting synaptogenesis, our knowledge about their intracellular mechanisms remains limited. H...

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Bibliographic Details
Main Authors: Xi Chen, Akihiro CE Shibata, Ardalan Hendi, Mizuki Kurashina, Ethan Fortes, Nicholas L Weilinger, Brian A MacVicar, Hideji Murakoshi, Kota Mizumoto
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
synapse
development
plexin
pattern formation
RAP2
genetics
Online Access:https://elifesciences.org/articles/38801

Internet

https://elifesciences.org/articles/38801

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