In vitro antiproliferative and apoptotic effects of thiosemicarbazones based on (-)-camphene and R-(+)-limonene in human melanoma cells.

In vitro antiproliferative and apoptotic effects of thiosemicarbazones based on (-)-camphene and R-(+)-limonene in human melanoma cells.

A series of 38 thiosemicarbazone derivatives based on camphene and limonene were evaluated for their antiproliferative activity. Among them, 19 were synthesized and characterized using proton and carbon-13 nuclear magnetic resonance (1H and 13C NMR). For initial compound selection, human melanoma ce...

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Bibliographic Details
Main Authors: Paula Roberta Otaviano Soares, Débora Cristina Souza Passos, Francielly Moreira da Silva, Ana Paula B da Silva-Giardini, Narcimário Pereira Coelho, Cecília Maria Alves de Oliveira, Lucília Kato, Cleuza Conceição da Silva, Lidia Guillo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295012&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295012&type=printable

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