Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation

Hepatitis B virus (HBV) relies on the core protein (HBc) to establish productive infection, as defined by the formation of the covalently closed circularized DNA (cccDNA), as well as to carry out almost every step of the lifecycle following cccDNA formation. Multiple copies of HBc form an icosahedra...

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Bibliographic Details
Main Authors: Megan A. Mendenhall, Xupeng Hong, Jianming Hu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/3/642