Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives

Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives

Due to the uneven distribution of glycosidase enzyme expression across bacteria and fungi, glycoside derivatives of antimicrobial compounds provide prospective and promising antimicrobial materials. Therefore, herein, we report the synthesis and characterization of six novel methyl 4,6-<i>O<...

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Bibliographic Details
Main Authors: Mohammad I. Hosen, Yousef E. Mukhrish, Ahmed Hussain Jawhari, Ismail Celik, Meryem Erol, Emad M. Abdallah, Mohammed Al-Ghorbani, Mohammed Baashen, Faisal A. Almalki, Hamid Laaroussi, Taibi Ben Hadda, Sarkar M. A. Kawsar
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
methyl 4,6-<i>O</i>-benzylidene-α-<span style="font-variant: small-caps">d</span>-glucopyranoside
antimicrobial
PASS prediction
molecular dynamics
POM theory
identification of pharmacophore sites
Online Access:https://www.mdpi.com/1420-3049/28/6/2613

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https://www.mdpi.com/1420-3049/28/6/2613

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