Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives

Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives

Due to the uneven distribution of glycosidase enzyme expression across bacteria and fungi, glycoside derivatives of antimicrobial compounds provide prospective and promising antimicrobial materials. Therefore, herein, we report the synthesis and characterization of six novel methyl 4,6-<i>O<...

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Manylion Llyfryddiaeth
Prif Awduron: Mohammad I. Hosen, Yousef E. Mukhrish, Ahmed Hussain Jawhari, Ismail Celik, Meryem Erol, Emad M. Abdallah, Mohammed Al-Ghorbani, Mohammed Baashen, Faisal A. Almalki, Hamid Laaroussi, Taibi Ben Hadda, Sarkar M. A. Kawsar
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2023-03-01
Cyfres:Molecules
Pynciau:
methyl 4,6-<i>O</i>-benzylidene-α-<span style="font-variant: small-caps">d</span>-glucopyranoside
antimicrobial
PASS prediction
molecular dynamics
POM theory
identification of pharmacophore sites
Mynediad Ar-lein:https://www.mdpi.com/1420-3049/28/6/2613

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https://www.mdpi.com/1420-3049/28/6/2613

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