Prediction of immunotherapy responsiveness in melanoma through single-cell sequencing-based characterization of the tumor immune microenvironment

Prediction of immunotherapy responsiveness in melanoma through single-cell sequencing-based characterization of the tumor immune microenvironment

Immune checkpoint inhibitors (ICB) therapy have emerged as effective treatments for melanomas. However, the response of melanoma patients to ICB has been highly heterogenous. Here, by analyzing integrated scRNA-seq datasets from melanoma patients, we revealed significant differences in the TiME comp...

Full description

Bibliographic Details
Main Authors: Yucheng Dong, Zhizhuo Chen, Fan Yang, Jiaxin Wei, Jiuzuo Huang, Xiao Long
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Translational Oncology
Subjects:
Immunotherapy
Machine learning
Melanoma
Single-cell sequencing
Tumor micro-environment
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000354

Internet

http://www.sciencedirect.com/science/article/pii/S1936523324000354

Similar Items