Bimodal distribution and set point HBV DNA viral loads in chronic infection: retrospective analysis of cohorts from the UK and South Africa [version 2; peer review: 2 approved]

Hepatitis B virus (HBV) viral load (VL) is used as a biomarker to assess risk of disease progression, and to determine eligibility for treatment. While there is a well recognised association between VL and the expression of the viral e-antigen protein, the distributions of VL at a population level a...

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Bibliographic Details
Main Authors: Louise O. Downs, Sabeehah Vawda, Phillip Armand Bester, Katrina A. Lythgoe, Tingyan Wang, Anna L. McNaughton, David A. Smith, Tongai Maponga, Oliver Freeman, Kinga A. Várnai, Jim Davies, Kerrie Woods, Christophe Fraser, Eleanor Barnes, Dominique Goedhals, Philippa C. Matthews
Format: Article
Language:English
Published: Wellcome 2020-10-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/5-113/v2