Cloning and expression heterologous alanine dehydrogenase genes: Investigation of reductive amination potential of L-alanine dehydrogenases for green synthesis of alanine derivatives

Cloning and expression heterologous alanine dehydrogenase genes: Investigation of reductive amination potential of L-alanine dehydrogenases for green synthesis of alanine derivatives

Unnatural amino acids (UAAs) offer significant promise in a wide range of applications, including drug discovery, the custom design of peptides and proteins, and their utility and use as markers for monitoring molecular interactions in biological research. The synthesis of UAAs presents a formidable...

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Bibliographic Details
Main Authors: Ğarip Demir, Jarkko Valjakka, Ossi Turunen, Fatih Aktaş, Barış Binay
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Unnatural amino acids
L-Alanine dehydrogenase
Reductive amination mechanism
Active site modelling
Green synthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402402930X

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http://www.sciencedirect.com/science/article/pii/S240584402402930X

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