Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression

Abstract Epithelial-mesenchymal transition (EMT) and proliferation play important roles in epithelial cancer formation and progression, but what molecules and how they trigger EMT is largely unknown. Here we performed spatial transcriptomic and functional analyses on samples of multistage esophageal...

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Bibliographic Details
Main Authors: Liping Chen, Shihao Zhu, Tianyuan Liu, Xuan Zhao, Tao Xiang, Xiao Hu, Chen Wu, Dongxin Lin
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01710-2